By John Kiwanuka
Ssemakula (MD, MPH), May 22, 2003
The SARS epidemic has generated a lot of scientific research
and interest into the origin of the virus and the epidemiology
of its spread. One of the more unusual features of this virus
that has emerged from the research of Asra
Ghani of the Department of Infectious
Disease Epidemiology at Imperial College, London. She found
that most people who get SARS do not infect anyone else, but
some individuals appeared to be responsible for transmitting
the disease to dozens and sometimes hundreds of others. Such
individuals are known as "superspreaders",
and these superspreaders have some
role in transmission of the disease.
Another disease that exhibits this kind of classic transmission
heterogeneity is HIV. In the case of HIV most people have
just a few sexual partners and so transmit the virus to one
or two other individuals, but a small number of people have
a large number of partners, and spread the virus widely. Such
a picture is supported by research in countries in Africa
that seems to suggest the majority of people have one or two
partners. In the case of HIV in Africa
individuals who would serve as classic “superspreaders”
are long distant truck drivers long suspected of being a factor
in the spread of HIV across borders in Africa,
or soldiers in times of conflict when a lot of sexual assaults
and rape take place such as happened in the genocide in Rwanda.
Further reading:
- BioMedNet Magazine 21st May - 3rd June 2003 - “SARS:
masking the real danger “ (requires free one time
registration to access articles)
- Donnelly C. A, Ghani A. C et al (2003). “Epidemiological
determinants of spread of causal agent of severe acute respiratory
syndrome in Hong Kong” The Lancet Volume 361, Number
9370. May (requires free one time registration to access
articles)
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