MALARIA

WHO MALARIA TREATMENT GUIDELINES: Global AMDP database - AFRO

P.falciparum

P.vivax

COUNTRY/AREA

SPECIES

uncomplicated

treatment failure

severe malaria

pregnancy

chloroquine

treatment failure

primaquine

unconfirmed

lab-confirmed

treatment

prevention

Algeria

vivax only

CQ 25 mg/kg

Angola

CQ 25mg/kg

CQ 25 mg/kg

SP

quinine 3 dd, 7d

CQ weekly

Benin

CQ 25mg/kg

CQ 25 mg/kg

SP

quinine 3 dd, 7d

CQ weekly

Botswana

SP

SP

quinine 3 dd, 7d

quinine 3 dd, 7d

SP- PIT

Burkina Faso

CQ 25mg/kg

CQ 25 mg/kg

SP

quinine 3 dd, 7d

CQ weekly

Burundi

SP

SP

quinine 3 dd, 7d

quinine 3 dd, 7d

SP - PIT

Cameroon

CQ 25 mg/kg

CQ 25 mg/kg

SP

quinine 3 dd, 7d

CQ weekly

AQ 25 mg/kg

AQ 25 mg/kg

Cape Verde

CQ 25mg/kg

CQ 25mg/kg

SP

quinine 3 dd, 7d

CQ weekly

Central African Republic

CQ 25mg/kg

CQ 25 mg/kg

SP

quinine 3 dd, 7d

CQ weekly

Chad

CQ 25mg/kg

CQ 25 mg/kg

SP

quinine 3 dd, 7d

CQ weekly

Comoros

CQ 25mg/kg

CQ 25mg/kg

SP

quinine 3 dd, 7d

CQ weekly

Congo Brazzaville

CQ 25mg/kg

CQ 25 mg/kg

SP

quinine 3 dd, 7d

CQ weekly

Côte d'Ivoire

CQ 25mg/kg

CQ 25 mg/kg

SP

quinine 3 dd, 7d

CQ weekly

Dem. Rep. of the Congo

SP

SP

quinine 3 dd, 7d

quinine 3 dd, 7d

SP- PIT

Equatorial Guinea

CQ 25mg/kg

CQ 25 mg/kg

SP

quinine 3 dd, 7d

CQ weekly

Eritrea

CQ 25mg/kg+SP

CQ 25mg/kg+SP

quinine 3 dd, 7d

quinine 3 dd, 7d

CQ weekly

Ethiopia

fal +vivax

CQ 25 mg/kg + SP

CQ 25mg/kg+SP

quinine 3 dd, 7d

quinine 3 dd, 7d

CQ + PG

CQ 25 mg/kg

SP- PIT

Gabon

falciparum

CQ 25mg/kg

CQ 25mg/kg

SP

quinine 3 dd, 7d

CQ weekly

Gambia

CQ 25mg/kg

CQ 25mg/kg

SP

quinine 3 dd, 7d

CQ weekly

Ghana

CQ 25mg/kg

CQ 25mg/kg

SP

quinine 3 dd, 7d

CQ weekly

Guinea

CQ 25mg/kg

CQ 25mg/kg

SP

quinine 3 dd, 7d

CQ weekly

Guinea-Bissau

CQ 25mg/kg

CQ 25mg/kg

SP

quinine 3 dd, 7d

CQ weekly

Kenya

SP

SP

AQ 25 mg/kg

quinine 3 dd, 7d

SP- PIT

Liberia

CQ 25mg/kg

CQ 25mg/kg

SP

quinine 3 dd, 7d

CQ weekly

Madagascar

CQ 25mg/kg

CQ 25mg/kg

SP

quinine 3 dd, 7d

CQ weekly

Malawi

SP

SP

quinine 3 dd, 7d

quinine 3 dd, 7d

SP- PIT

Mali

CQ 25mg/kg

CQ 25 mg/kg

SP

quinine 3 dd, 7d

CQ weekly

Mauritania

CQ 25mg/kg

CQ 25mg/kg

SP

quinine 3 dd, 7d

CQ weekly

Mauritius

vivax only

CQ 25 mg/kg

Mayotte (Fr.)

Mozambique

CQ 25mg/kg

CQ 25mg/kg

SP

quinine 3 dd, 7d

CQ weekly

Namibia

CQ 25mg/kg

CQ 25mg/kg

SP

quinine 3 dd, 7d

CQ weekly

Niger

CQ 25mg/kg

CQ 25mg/kg

SP

quinine 3 dd, 7d

CQ weekly

Nigeria

CQ 25mg/kg

CQ 25mg/kg

SP

quinine 3 dd, 7d

CQ weekly

Rwanda

AQ + SP(2001)

AQ + SP

quinine 3 dd, 7d

quinine 3 dd, 7d

CQ weekly

Sao Tome and Principe

CQ 25mg/kg

CQ 25mg/kg

SP

quinine 3 dd, 7d

CQ weekly

Senegal

CQ 25mg/kg

CQ 25mg/kg

SP

quinine 3 dd, 7d

CQ weekly

Sierra Leone

CQ 25mg/kg

CQ 25mg/kg

SP

quinine 3 dd, 7d

CQ weekly

South Africa

Coartem (Kwazulu Natal); SP

Coartem (Kwazulu Natal); SP

quinine 3 dd, 7d

quinine 3 dd, 7d

CQ + PG

Swaziland

CQ 25mg/kg

CQ 25mg/kg

SP

quinine 3 dd, 7d

CQ weekly

Togo

CQ 25mg/kg

CQ 25mg/kg

SP

quinine 3 dd, 7d

CQ weekly

Uganda

CQ 25mg/kg +SP

CQ 25mg/kg +SP

quinine 3 dd, 7d

quinine 3 dd, 7d

CQ weekly

United Republic of Tanzania

SP

SP

AQ 30mg/kg

quinine 3 dd, 7d

SP - PIT

Zambia

CQ 25mg/kg

CQ 25mg/kg

SP

quinine 3 dd, 7d

CQ weekly

Zanzibar

Artesunate + AQ

Artesunate + AQ

Artemether-lumefantrine

quinine 3 dd, 7d

SP - PIT

Zimbabwe

CQ 25mg/kg (+SP in 2 districts)

CQ 25mg/kg (+SP in 2 districts

SP

quinine 3 dd, 7d

Maloprim weekly

CQ= Chloroquine

SP= sulfadoxine and pyrimethamine (Fansidar)

Coartem = artemether + lumefantrine – Artemisinin derivative

Artenusate - Artemisinin derivative